A case of lupus-like glomerulonephritis in an HIV patient with nephrotic range proteinuria, purpura, and elevated IgA level

作者：Yang Jihyun; Seo Min Young; Kim Ki Tae; Lee Jun Yong; Kim Sun Chul; Kim Myung Gyu; Jo Sang Kyung; Cho Won Yong; Kim Hyoung Kyu; Won Nam Hee; Cha Ran Hui; Cho Eunjung^*

来源：International Journal of Clinical and Experimental Pathology, 2014, 7(7): 4467-4472.

• Human immunodeficiency virus
• glomerulonephritis
• HIV-associated nephropathy
• lupus nephritis
• renal biopsy

Human immunodeficiency virus (HIV) infection is growing medical concern worldwide. There are many types of glomerulonephritis which are associated with HIV infection. We report a case of a 53-year-old Korean man with an HIV infection, who was developed nephritic range proteinuria and purpura with elevated IgA level rasing a possibility of Henoch-Scholein Purpura (H-S purpura). However, renal biopsy showed "lupus-like feature" glomerulonephritis without clinical or serologic evidence of systemic lupus erythematosus. Although baseline renal function was maintained without further need for maintenance dialysis following anti-retroviral therapy (ART) and steroid, patient died from uncontrolled gastrointestinal bleeding.

• 出版日期2014