科研之友
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摘要
An efficient and novel method for the synthesis of pyrazolo[3,4-f]quinoline derivatives by an efficient in situ reduction and cyclization reaction of 6-nitro-1H-indazole, aromatic aldehydes, and 4-hydroxy-2H-chromen-2-one or barbituric acid has been developed. Compared with amino compounds, nitro compounds are easier to obtain and more stable. The synthesis was achieved by using a multicomponent procedure under Fe/H2O medium. The advantages of this method are mild conditions, operational simplicity, high yields, and wide range of substrates.
- 出版日期2018-12
- 单位南京医科大学
