科研之友
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摘要
Available data on the reductive alkylation of amines with carbonyl compounds a key method for the preparation of secondary and tertiary amines - are described systematically. The review provides information on the relevant reducing agents and catalysts and on the use of chiral catalysts in stereo- and enantiocontrolled reactions of amine synthesis. The effect of the reactant and catalyst structures on the reaction rates and chemo- and stereo(enantio)selectivity is considered.
- 出版日期2015
