Antiviral Activity of Obtained Extracts from Different Parts of Cupressus sempervirens against Herpes Simplex Virus Type 1

作者：Emami Seyed Ahmad; Tayarani Najaran Zahra; Ghannad Masoud Sabouri; Karamadini Pezhman Khajeh; Karamadini Mehrangiz Khajeh^*

来源：Iranian Journal of Basic Medical Sciences, 2009, 12(3-4): 133-139.

• Antiviral activity
• Cupressus sempervirens
• Cupressusaceae
• HSV-1

Objective(s)
The aim of this study was to search for new antiviral agents from herbal medicines. Ethanol extracts of C semipervirens, C semipervirens var. horizontalis and C semipervirens cv. Cereiformis were used in experiments to test their influence on herpes viruses (HSV-1).
Materials and Methods
HeLa cells monolayers were infected with herpes viruses (HSV-1). Antiviral activity of the plant extracts assessed using Hematoxylin & Eosin method and observed under a light microscope. All tests were compared with a positive control, acyclovir.
Results
Results showed that all three plants have antiviral activity against HSV-1 virus. The most active extract was the obtained extract from C. semipervirens. Among the different parts of this medicinal plant tested, the fruit's extract appeared to possess the strongest anti- HSV activity.
Conclusion
In conclusion, of the extracts tested in this survey all showed significant antiviral potency.

• 出版日期2009