Application of graphite screen printed electrode modified with dysprosium tungstate nanoparticles in voltammetric determination of epinephrine in the presence of acetylcholine

作者：Beitollahi Hadi^*; Dourandish Zahra; Tajik Somayeh; Ganjali Mohammad Reza; Norouzi Parviz; Faridbod Farnoush

来源：Journal of Rare Earths, 2018, 36(7): 750-757.

DOI：10.1016/j.jre.2018.01.010

• Epinephrine
• Acetylcholine
• Dy-2(WO4)(3) nanoparticles
• Graphite screen printed electrode
• Rare earths

The current work focuses on the development of a sensitive and selective electrochemical device based on a graphite screen printed electrode modified with Dy-2(WO4)(3) nanoparticles (DWO/SPE) for the analysis of epinephrine in samples also containing acetylcholine. The study proves that the sensor has excellent electron-mediating behavior in the oxidation of epinephrine in a 0.1 mol/L phosphate buffer solution (PBS) (pH 7.0). The application of the DWO/SPE in differential pulse voltammetry (DPV) is found to lead to distinct response for the oxidation of epinephrine and acetylcholine, with the potentials of the epinephrine and acetylcholine peaks (Delta E-p) to be 550 mV apart. The detection limits of the method for epinephrine and acetylcholine are 0.5 and 0.7 mu mol/L (S/N = 3) and the responses are found to be linear in the concentration ranges of 1.0-900.0 mu mol/L and 1.0-1200.0 mu mol/L in a PBS buffer (pH = 7.0) respectively. The modified electrode was used for the detection of epinephrine and acetylcholine in real samples and found to produce satisfactory results. These results can be a proof that Dy-2(WO4)(3) nanoparticles can find promising applications in electrochemical sensors to be used for the analysis of (bio) chemical species.

• 出版日期2018-7