Arylative Desulfonation of Diarylmethyl Phenyl Sulfone with Arenes Catalyzed by Scandium Triflate

作者:Nambo Masakazu*; Ariki Zachary T; Canseco Gonzalez Daniel; Beattie D Dawson; Crudden Cathleen M*
来源:Organic Letters, 2016, 18(10): 2339-2342.
DOI:10.1021/acs.orglett.6b00744

摘要

A scandium-triflate-catalyzed arylative desulfonation of diarylmethyl phenyl sulfones with arenes and heteroarenes was established. A variety of both sulfone and arene substrates were reacted to afford symmetric and nonsymmetric triarylmethanes in good yields. Further transformations of the resulting triarylmethanes and application to the concise synthesis of a bactericidal agent analogue were also demonstrated.

  • 出版日期2016-5-20