A Modular Approach to Pressurized Liquid Extraction with In-Cell Cleanup

作者：Haglund Peter^*; Spinnel Erik

来源：LC-GC North America, 2011, 66-72.

A new concept for the extraction of solid samples has been developed. The popular pressurized liquid extraction (PLE) technique has been modified so that the extraction cell can be divided, which greatly increases the flexibility and versatility of this technique. The system uses simple adapters to couple commercially available extraction cells, which can be loaded with either sample or adsorbents. These segmented extraction cells make it possible to selectively retain analytes or matrix to achieve simultaneous extraction and cleanup or fractionation. The ultimate aim is to perform simultaneous extraction and cleanup and obtain a purified extract that is ready for instrumental analysis, all in line with current trends in analytical chemistry to automate and streamline the analytical procedures to reduce the analysis costs, solvent consumption, and manual labor, and increase the quality of analysis. Selected modes of operations are presented and a few recent environmental applications of modular PLE are reviewed.

• 出版日期2011-2