A 3-YEAR- OLD GIRL WITH ALTERED MENTAL STATUS, GAIT DIFFICULTY, AND VOMITING

作者:Lim Ilya; Mikolaenko Irina*; Cohen Mark
来源:Brain Pathology, 2011, 21(1): 105-108.
DOI:10.1111/j.1750-3639.2010.00450.x

摘要

We report a case of a 3-year-old girl with a 9-month history of focal neurologic finding and signs of increased intracranial pressure. Radiological imaging studies showed a minimally heterogeneous enhancing large tumor involving left parietal region and partly filling the left lateral ventricle. Microscopically, the tumor contained prominent small true rosettes set into areas of fibrillar neuropil-like matrix. Foci of cellular tumor with extensive apoptosis were present. The neuropil-like areas and true rosettes were positive for synaptophysin immunostain. The tumor was negative for GFAP and neurofilament protein immunostains. MIB-1 proliferation index was high focally approaching 80%.

  • 出版日期2011-1