A novel method for the synthesis of 3,4-disubstitutedpyrrole-2,5-dicarboxylates from hydrazones derived from alpha-diazo esters

作者：Yasui Eiko^*; Wada Masao; Nagumo Shinji; Takamura Norio

来源：Tetrahedron, 2013, 69(21): 4325-4330.

DOI：10.1016/j.tet.2013.03.037

• Pyrrole
• Piloty-Robinson pyrrole synthesis
• alpha-Diazo ester
• Hydrazone

Hydrazones obtained from alpha-diazo esters were converted to pyrroles when heated with thionyl chloride in alcohol. Among hydrazones, those substituted with a benzene ring on the beta-carbon to the ester are likely to give pyrroles in good yields.

• 出版日期2013-5-27