Adaptation and validation of the Spanish version of a disease-specific quality of life measure in patients with systemic lupus erythematosus: The Lupus Quality of Life

作者：Gonzalez Rodriguez Viviana; Isabel Peralta Ramirez Maria; Navarrete Navarrete Nuria; Luis Callejas Rubio Jose; Santos Ruiz Ana Maria; Khamashta Munther

来源：Medicina Clinica, 2010, 134(1): 13-16.

DOI：10.1016/j.medcli.2009.04.045

• Lupus Quality of Life
• Systemic lupus erythematosus
• Quality of life

Background and objective: Systemic Lupus Erythematosus (SLE) is an auto-immune disease that seriously affects quality of life. There are various specific instruments that measure health-related quality of life (HRQOL), but none of them has been adapted to Spanish. We intended to adapt and validate in a Spanish population a specific HRQOL measure in patients with SLE.
Patients and methods: The adaptation was carried out using the translation and back-translation method of the English version of the LupusQoL, with its subsequent application to 115 adults with SLE.
Results: The factorial analysis identified 5 domains of the LupusQoL; the reliability tests showed a high Cronbach alpha coefficient of 0.977 and a high Guttman two-halves coefficient of 0.936; the significant correlations of the LupusQoL with the SF-36 showed a high convergent validity of the questionnaire; in addition, the correlations with the SLEDAI and SLICC were low, which showed its discriminated validity.
Conclusion: The Spanish version of the LupusQoL has stable psychometric properties to measure HRQOL in people with SLE in clinical and research settings in a Spanish-speaking population.

• 出版日期2010-1-23