Urolithiasis: What can we learn from a Nature which dysfunctions?

作者:Bazin Dominique*; Portehault David; Tielens Frederik; Livage Jacques; Bonhomme Christian; Bonhomme Laure; Haymann Jean Philippe; Abou Hassan Ali; Laffite Guillaume; Frochot Vincent; Letavernier Emmanuel; Daudon Michel
来源:Comptes Rendus Chimie, 2016, 19(11-12): 1558-1564.
DOI:10.1016/j.crci.2016.01.019

摘要

Learning from Mother Nature constitutes a major intellectual movement encompassing music, architecture and chemistry. In this contribution, we would like to assess the symmetry and the interface present in pathological calcifications in order to propose a bio-inspired approach. We present an overview on the observations made on kidney stone growth at the macroscopic scale. The results are discussed at the molecular scale and examples are proposed to implement the biological asymmetrical growth in pathological calcifications in biomimetic strategies such as in in vitro microfluidic experiments.

  • 出版日期2016-12

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