Effects of soy milk consumption on inflammatory markers and lipid profiles among non-menopausal overweight and obese female adults

作者：Nourieh Zeinab; Keshavarz Seyed Ali; Attar Mohammad Javad Hosseinzadeh; Azadbakht Leila^*

来源：Journal of Research in Medical Sciences, 2012, 17: S65-S72.

• Soy Milk
• Inflammation
• Obese
• Overweight
• Females

BACKGROUND: Few studies have evaluated the effects of soy milk replacement in the diet on inflammatory markers among non-menopausal overweight and obese female adults. We evaluated the effects of soy milk compared to cow%26apos;s milk on inflammation and lipid profiles among non-menopausal overweight and obese female adults. METHODS: This cross-over randomized clinical trial was conducted on 24 overweight or obese women. There were two 4-week trial periods (soy milk period and cow%26apos;s milk period). In the soy milk period, only one glass of soy milk (240 cc) was replaced instead of one glass of cow%26apos;s milk (240 cc). RESULTS: Fat contents in soy milk and cow%26apos;s milk were 1 g per 100 ml and 1.5 g per 100 ml, respectively. Serum low density lipoprotein (LDL) level reduced significantly following soy milk period (mean percent change in soy milk period vs. cow%26apos;s milk period: -11.22 +/- 3.85% vs. -1.18 +/- 2.82%; p = 0.01). Inflammatory factors and other lipid profiles did not change significantly after the soy milk period compared to the cow%26apos;s milk period. In addition, soy milk could not reduce the weight of non-menopausal overweight and obese female adults. CONCLUSION: Soy milk replacement had beneficial effects on LDL levels in a short term trial among overweight and obese women. However, it had no significant effects on inflammatory markers and other lipid profiles among these non-menopausal overweight and obese adults.

• 出版日期2012-3