A longitudinal study of comparison of the Kato-Katz technique and indirect hemagglutination assay (IHA) for the detection of schistosomiasis japonica in China, 2001-2006

作者：Zhou Yi Biao^*; Yang Mei Xia; Tao Po; Jiang Qiu Lin; Zhao Gen Ming; Wei Jian Guo; Jiang Qing Wu

来源：Acta Tropica, 2008, 107(3): 251-254.

DOI：10.1016/j.actatropica.2008.06.009

• Schistosomiasis
• Schistosoma japonicum
• Kato-Katz technique
• Prevalence
• Indirect hemagglutination assay (IHA)
• Diagnosis
• Comparative study
• China

From 2001 to 2006, about one-third of the residents aged 5-65 years were selected as the subjects in a schistosome-endemic village located in Jiangxi Province, China. Every I year, all participants were analyzed by the Kato-Katz parasitologic examination and indirect hemagglutination assay (IHA). Statistical analysis of the results showed the k indices ranged from 0.250 to 0.347 between the two methods. Assuming the Kato-Katz results as the gold standard reference, the specificity of the IHA was from 60% to 77%, the positive predictive value of this method was from 19% to 30%, and its sensitivity and negative predictive value were more than 97%. The IHA method is unsuitable for individual screening in endemic community with relatively high prevalence (e.g. with > 10% or more prevalence). A search for a better diagnostic test that can be applied in field situations in China is essential and should be given high priority.

• 出版日期2008-9
• 单位复旦大学