An efficient diastereoselective one-pot synthesis of functionalized dihydropyrrolo[1,2-a]quinolines

作者：Yavari Issa^*; Aminkhani Ali; Skoulika Stavroula

来源：Journal of the Iranian Chemical Society, 2013, 10(1): 107-111.

DOI：10.1007/s13738-012-0130-3

• Bridgehead N-heterocycles
• MCRs
• Isocyanide
• Benzaldehydes
• Malononitrile
• Quinoline

A diastereoselective synthesis of 2-aryl-1-(cyclohexylimino)-1,2-dihydropyrrolo[1,2-a]quinoline-3,3(3aH)-dicarbonitriles is developed through a one-pot four-component reaction of malononitrile, benzaldehydes, quinoline and cyclohexyl isocyanide in a simple, mild, and efficient protocol.

• 出版日期2013-2