Participation of ethyl 3-formylindole-2-carboxylate with the Ugi four-component condensation reaction

作者：Shiri Morteza^*; Zolfigol Mohammad Ali; Khazaei Ardeshir; Faal Rastegar Toktam; Kruger Hendrik G

来源：Journal of the Iranian Chemical Society, 2014, 11(1): 85-90.

DOI：10.1007/s13738-013-0278-5

• Condensation
• Dipeptides
• Indole
• Multicomponent reactions
• Amines

Multicomponent condensation of ethyl 3-formylindole 2-carboxylate, amines, isocyanide and (S)-N-boc-alanine or (S)-N-boc-serine is described. This Ugi four-component condensation (Ugi-4CC) reaction yielded a series of novel dipeptides containing an indolyl moiety. These compounds exhibit potential biological activity.

• 出版日期2014-2