Atypical Fetal Response to the Mother%26apos;s Voice in Diabetic Compared With Overweight Pregnancies

作者：Kisilevsky Barbara S^*; Gilmour Antonella; Stutzman Sherri S; Hains Sylvia M J; Brown C Ann

来源：Journal of Developmental and Behavioral Pediatrics, 2012, 33(1): 55-61.

DOI：10.1097/DBP.0b013e31823e791e

• fetus
• heart rate
• audition
• voice
• diabetes
• obesity

Objective: To characterize fetal spontaneous heart rate changes and movements and auditory-elicited heart rate changes in fetuses in diabetic pregnancies compared with those in uneventful, overweight pregnancies. Methods: Spontaneous heart rate and movements and maternal voice-elicited heart rate changes were observed in 46 mother-fetal pairs (n = 14 gestational diabetic and n = 32 overweight prepregnancy) at 36 (+/- 1) weeks gestational age. Fetal heart rate changes, body movements, and breathing movements were observed for 20 minutes while the mother was at rest. Subsequently, each fetus was presented with a 2-minute audio recording of the mother%26apos;s voice using the following 6-minute procedure: 2 minutes no-voice baseline, 2 minutes voice presentation, and 2 minutes no-voice postvoice period; heart rate was recorded continuously. Results: There were no differences in spontaneous heart rate changes, body movements, or breathing movements between the 2 groups. Fetuses in the overweight group showed an increase in the heart rate during the playing of their mother%26apos;s voice, whereas fetuses in the diabetic group showed no response. Conclusions: Fetuses in overweight pregnancies responded to the mother%26apos;s voice with an increase in the heart rate as has been reported previously in uneventful pregnancies. The lack of response to the mother%26apos;s voice in fetuses in diabetic pregnancies may represent immature neural or auditory system development, an increased sensorineural threshold, and thyroid or iron deficiency.

• 出版日期2012-1