Double-balloon enteroscopy for diagnosis of Meckel's diverticulum: Comparison with operative findings and capsule endoscopy

作者:He, Qiong; Zhang, Ya-li; Xiao, Bing; Jiang, Bo; Bai, Yang; Zhi, Fa-chao*
来源:Surgery, 2013, 153(4): 549-554.
DOI:10.1016/j.surg.2012.09.012

摘要

Background. Meckel's diverticulum (MD) is one of the most common congenital gastrointestinal malformations. It is difficult to make a preoperative diagnosis of MD. To date, few data are available describing the diagnosis of MD by double-balloon enteroscopy (DBE) and capsule endoscopy (CE). @@@ Methods. To assess the value of DBE in the diagnosis of MD and comparatively evaluate the diagnostic yield of DBE and CE for MD. A single-center study was performed on patients with a confirmed diagnosis of MD by surgery and postoperative pathology between January 2003 and December 2011. @@@ Results. Seventy-four patients (60 males) with a mean age of 29.0 +/- 14.3 years were analyzed; 33 (55.0%) were between 21 and 40 years of age. Gastrointestinal bleeding was the major finding in 86.5% of the patients who were referred for DBE or CE examination. The mean duration of symptoms was 32.3 +/- 48.7 months. In the 74 patients, the diagnostic yield of DBE for MD before surgery was 86.5% (64/74), and correct diagnoses were made in the majority of cases by retrograde DBE, with a few cases by antegrade DBE. In the 26 patients undergoing CE before DBE, the overall diagnostic yield of DBE was 84.6%, significantly greater than that of CE (7.7%, P <.000, McNemar's x(2) test). Poor agreement was found between the 2 modalities (kappa = 0.03). @@@ Conclusion. For patients who are highly suspected of having MD, DBE provides a safe, effective, and reliable means of diagnosis before surgery. (Surgery 2013;153:549-54.)