A Concise Access to C-2-Symmetric Chiral 4-Pyrrolidinopyridine Catalysts with Dual Functional Side Chains

作者：Mishiro Kenji; Takeuchi Hironori; Furuta Takumi; Kawabata Takeo^*

来源：Chemical & Pharmaceutical Bulletin, 2016, 64(7): 1073-1077.

DOI：10.1248/cpb.c16-00292

• organocatalyst
• C-2-symmetry
• pyrrolidinopyridine
• catalyst library
• racemic precursor

A practical method was developed for the preparation of a diastereomeric library of C-2-symmetric chiral 4-pyrrolidinopyridine catalysts with dual amide side chains. Use of a racemic precursor is the key to the concise production of catalysts with diverse stereochemisty.

• 出版日期2016-7