Comparison of mammography, ultrasound, and MRI in size assessment of ductal carcinoma in situ with histopathologic correlation

作者：Baek Soo Heui; Choi Woo Jung^*; Cha Joo Hee; Kim Hak Hee; Shin Hee Jung; Chae Eun Young

来源：Acta Radiologica, 2017, 58(12): 1434-1441.

DOI：10.1177/0284185117698860

• Ductal carcinoma in situ
• mammography
• ultrasound
• magnetic resonance imaging (MRI)
• tumor size

Background: The ability to accurately assess tumor size in ductal carcinoma in situ (DCIS) is an important clinical issue when selecting the appropriate treatment plan.
Purpose: To compare the accuracy of using mammography, ultrasound (US), and magnetic resonance imaging (MRI) to assess DCIS tumor size based on imaging and histopathological findings.
Material and Methods: Fifty-six patients with DCIS were included. Mammography, US, and MRI were reviewed, and the accuracy of the measured tumor sizes were compared with the imaging and histopathological parameters.
Results: If visible, tumor measurements demonstrated high reliability with the pathologically determined size, with the best results obtained using US (k = 0.851) followed by mammography (k = 0.815) and MRI (k = 0.738). Tumor size assessment was significantly more accurate when the lesion was shown as a mass on US (P = 0.003) or MRI (P < 0.001) with minimal and mild background parenchymal enhancement (P = 0.016) on MRI. When mammography was used to assess tumor size, the tumors with positive estrogen receptor status and luminal A subtype demonstrated a significantly more accurate tumor size.
Conclusion: The combination of US and MRI, in addition to mammography, has an important role in assessing the exact tumor extent of DCIS.

• 出版日期2017-12