A Pilot Respiratory Health Assessment of Nail Technicians: Symptoms, Lung Function, and Airway Inflammation

作者：Reutman Susan R^*; Rohs Amy M; Clark John C; Johnson Belinda C; Sammons Deborah L; Toennis Christine A; Robertson Shirley A; MacKenzie Barbara A; Lockey James E

来源：American Journal of Industrial Medicine, 2009, 52(11): 868-875.

DOI：10.1002/ajim.20751

• nail technicians
• artificial nails
• lung function
• exhaled nitric oxide
• smoking

Background Recent surveys suggest nail technicians, particularly artificial nail applicators, have increased respiratory symptoms and asthma risk.
Methods We examined lung n = 62) and a marker of airway inflammation, i.e., exhaled nitric oxide (ENO) (n = 43), in a subset of nail technician and control participants in a pilot health assessment.
Results Bivariate analysis of technicians demonstrated that job latency was inversely correlated with FEV1 percent predicted (FEV1PP) (r = -0.34, P = 0.03) and FVCPP (r = -0.32, P = 0.05). Acrylic gel contact hours were inversely correlated with FEV1PP (r = -0.38, P = 0.02) and FVCPP (r = -0.47, P = 0.003). Current smoking was inversely and significantly (P <= 0.05) associated with ENO in bivariate analysis. Log 10 ENO levels were directly correlated with job latency (P = 0.012) and gel nail application (P = 0.026) in multivariable analyses.
Conclusions These positive pilot respiratory test results warrant additional future investigation. Am. J. Ind. Med. 52:868-875, 2009.

• 出版日期2009-11