Lamesticumin G, a new alpha-glucosidase inhibitor from the fruit peels of Lansium parasiticum

作者：Potipiranun Thammatee; Worawalai Wisuttaya; Phuwapraisirisan Preecha^*

来源：Natural Product Research, 2018, 32(16): 1881-1886.

DOI：10.1080/14786419.2017.1354184

• Lamesticumin G
• Lansium parasiticum
• Meliaceae
• triterpenoid
• alpha-glucosidase
• onoceranoid
• diabetes

A novel onoceranoid triterpene, named lamesticumin G (1) along with four known compounds (2-5) were isolated from the ethyl acetate extract of the fruit peels of Lansium parasiticum. The structure of lamesticumin G (1) was fully characterised using spectroscopic data. Lamesticumin G (1) inhibited alpha-glucosidase (maltase) with IC50 value of 2.27 mM, while 2-5 showed no inhibition.
[GRAPHICS]
.

• 出版日期2018