Uronephrological outcomes of patients with neural tube defects Does a spina bifida clinic make a difference?

作者：Al Hazmi Hamdan H^*; Trbay Mahmoud S; Gomha Abdulmonem B; Elderwy Ahmad A; Khatab Amenah J; Neel Khalid F

来源：Saudi Medical Journal, 2014, 35: S64-S67.

Objectives: To review the uronephrological outcomes of myelomeningocele) MMC(patients attending a Spina Bifida Clinic. %26lt;br%26gt;Methods: We retrospectively reviewed the medical records of all patients from the combined Spina Bifida Clinic, at King Khalid University Hospital, Riyadh, Saudi Arabia between 1999 and 2009 who had at least one year of follow-up with us. We examined their demographic data, uronephrological status at presentation, most recent follow-up, and the rate of surgical intervention. %26lt;br%26gt;Results: During the 10-year period, 188 patients were actively followed-up. The mean age at presentation was 5.3 years +/- 3.6 SD. At their last follow-up, 109 patients (58%) were using clean intermittent catheterization, 44 (23%) had received Botox (R) injections, and 26 (14%) had undergone bladder reconstruction. Most (66%) patients were older than 3 years when they presented to us; this group had a significantly higher rate of surgical intervention (Botox (R) or reconstruction) compared with those who came to us earlier (p=0.003 for patients receiving Botox (R) injections, and p=0.025 for patients undergoing bladder reconstruction). %26lt;br%26gt;Conclusion: Our multidisciplinary Spina Bifida Clinic is an integral part of MCC management to reach a safe urological outcome. Early presentations to our clinic resulted in a lesser need for surgical intercession compared with those who presented at more than 3 years old.

• 出版日期2014