DEVELOPMENT OF THE S3PVAC VACCINE AGAINST PORCINE TAENIA SOLIUM CYSTICERCOSIS: A HISTORICAL REVIEW

作者:Sciutto Edda*; Fragoso Gladis; Hernandez Marisela; Rosas Gabriela; Martinez Jose J; Fleury Agnes; Cervantes Jacquelynne; Aluja Aline; Larralde Carlos
来源:The Journal of Parasitology, 2013, 99(4): 686-692.
DOI:10.1645/GE-3102.1

摘要

Herein we present a review of our research dealing with vaccination against experimental and naturally acquired porcine Taenia solium cysticercosis using Taenia crassiceps-derived antigens. Results strongly support that the different versions of S3Pvac vaccine are indeed effective against porcine T. solium cysticercosis. Immunological results related to vaccination prove that protection is at least partially mediated by specific immunity. The data also support the validity of T. crassiceps murine cysticercosis as an effective tool to identify vaccine candidates against some metacestode infections.

  • 出版日期2013-8