A Novel Synthesis of Thioglycolurils by Ring Contraction of 5,7-Dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones

作者：Gazieva Galina A^*; Poluboyarov Pavel A; Popov Leonid D; Kolotyrkina Natalya G; Kravchenko Angelina N; Makhova Nina N

来源：Synthesis, 2012, 44(21): 3366-3370.

DOI：10.1055/s-0032-1317194

• N-heterocycles
• thioglycolurils
• 3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones
• aromatic aldehydes
• ring contraction

A new synthetic route to (E)-1,3-dialkyl-4-(benzylideneamino)-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones (thioglycolurils), by a ring contraction reaction of 5,7-dialkyl-3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones with aromatic aldehydes, has been developed.

• 出版日期2012-11