Authentication of food allergens

作者：Hoffmann Sommergruber Karin^*

来源：Journal of the Serbian Chemical Society, 2013, 78(3): 315-320.

DOI：10.2298/JSC121022002H

• food allergens
• IgE
• diagnosis

Pure allergen batches are required for precise personalised diagnosis of food allergies. Furthermore, they can be used to develop sensitive allergen detection assays in foods and are valuable tools to develop novel immune-therapies. However, these reagents have to be well characterised and have to meet certain quality criteria. Within the EU-Project EuroPrevall, the concept of an allergen library comprising the most important food allergens from animal- and plant-derived foods was developed together with a catalogue of physicochemical and immunological properties that had to be investigated. In close cooperation, partners from academia and the biotech industry applied well-established laboratory techniques as well as novel high throughput assays to analyse the most important features of the final protein batches. It is expected that this proof of concept will contribute to improved authentication of allergens for both routine application in allergy diagnosis and treatment and risk assessment in food production.

• 出版日期2013