Antihyperglycemic effects of ginseng and possible mechanisms

作者：Peng D C; Chen W P; Xie J T^*

来源：Drugs of the Future, 2008, 33(6): 507-514.

DOI：10.1358/dof.2008.033.06.1188424

Ginseng is a medicinal plant valued throughout the world and is considered the king of herbs in traditional Chinese/Oriental medicine. Ginseng has gained popularity as a dietary supplement in the United States and Canada in recent decades. The multiple constituents of ginseng possess equally multifaceted pharmacological functions, as demonstrated by numerous studies. According to previous reports, ginseng root and its constituents influence the central nervous system (CNS), endocrine, cardiovascular, gastrointestinal, sexual, renal and immune systems, etc. One important function of the ginseng plant is its antihyperglycemic effect. Ginseng extracts have been commonly used in Chinese/Oriental medicine to treat diabetes-like conditions. Our recent data suggest that all the main parts of the ginseng plant (including berry, root, leaf and stem) exhibit potent anti hyperglycemic effects and may provide an opportunity to develop a novel class of antidiabetic agents. In the current article, we focus on the antihyperglycemic effects of ginseng root, berry and leaf extracts, as well as on the possible mechanisms of the antihyperglycemic action.

• 出版日期2008-6
• 单位河北医科大学