MR Fingerprinting Using the Quick Echo Splitting NMR Imaging Technique

作者：Jiang Yun; Ma Dan; Jerecic Renate; Duerk Jeffrey; Seiberlich Nicole; Gulani Vikas; Griswold Mark A^*

来源：Magnetic Resonance in Medicine, 2017, 77(3): 979-988.

DOI：10.1002/mrm.26173

• MR fingerprinting
• QUEST
• quantitative imaging
• relaxation time
• specific absorption rate

Purpose: The purpose of the study is to develop a quantitative method for the relaxation properties with a reduced radio frequency (RF) power deposition by combining magnetic resonance fingerprinting (MRF) technique with quick echo splitting NMR imaging technique (QUEST).
Methods: A QUEST-based MRF sequence was implemented to acquire high-order echoes by increasing the gaps between RF pulses. Bloch simulations were used to calculate a dictionary containing the range of physically plausible signal evolutions using a range of T-1 and T-2 values based on the pulse sequence. MRF-QUEST was evaluated by comparing to the results of spin-echo methods. The specific absorption rate (SAR) of MRF-QUEST was compared with the clinically available methods.
Results: MRF-QUEST quantifies the relaxation properties with good accuracy at the estimated head SAR of 0.03 W/kg. T-1 and T-2 values estimated by MRF-QUEST are in good agreement with the traditional methods.
Conclusions: The combination of the MRF and the QUEST provides an accurate quantification of T-1 and T-2 simultaneously with reduced RF power deposition. The resulting lower SAR may provide a new acquisition strategy for MRF when RF energy deposition is problematic.

• 出版日期2017-3