ADDITIVE EFFECTS ON ASYMMETTRIC HYDROGENATION OF N-HETEROAROMATICS

作者：Nagano Takuto^*; Iimuro Atsuhiro; Yamaji Kenta; Kita Yusuke; Mashima Kazushi

来源：Heterocycles, 2014, 88(1): 103-127.

DOI：10.3987/REV-13-SR(S)2

• Asymmetric Hydrogenation
• Additive Effect
• Heteroaromatic Compound

The multiplication of chiral information is one of the most important tasks in organic chemistry. Chiral catalysis is the most elegant way to achieve this and organic chemists developed a variety of catalytic asymmetric reaction systems, in which the addition of some chemicals effectively improves the performance of transition-metal-catalysis. In this review, we summarize development of additive effects in the asymmetric hydrogenation of N-heteroaromatic compounds based on interactions of additives with catalysts and substrates.

• 出版日期2014-1-1