An efficient synthesis of 2-alkylthio-3-alkyl-5-furfurylidene-4H-imidazol-4-ones

作者:Sun Y*; Gao LP; Ding MW
来源:Heterocyclic Communications, 2006, 12(1): 25-28.
DOI:10.1515/HC.2006.12.1.25

摘要

2-Alkylthio-3-alkyl-5-furfurylidene-4H-imidazol-4-ones (4) under bar were synthesized by N-alkylation and S-alkylation of 2-thioxo-5-furfurylidene-4-imidazolidinone (3) under bar, which was obtained via cyclization of vinyl isothiocyanate (2) under bar with excess ammomium hydroxide (28% NH3 in water).

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