Acetyltrimethylsilane mediated synthesis of dihydrophenanthrenes

作者：Pratap Ramendra; Ram Vishnu Ji^*

来源：Tetrahedron Letters, 2007, 48(36): 6318-6320.

DOI：10.1016/j.tetlet.2007.07.014

• acetyltrimethylsilane
• dihydrophenanthrene
• 2-oxobenzo[h] chromenes
• ring transformation

An easy and efficient synthesis of phenanthrene derivatives through base catalyzed ring transformation of 4-sec-amino-2oxo-5,6-dihydro-2H-benzo[h]chromene-3-carbonitrites with acetyltrimethylsilane is described in good yields. The advantage of this reaction is the direct transformation of 2-oxobenzo[h]chromene into phenanthrene via C-C insertion from acetyltrimethylsilane.

• 出版日期2007-9-3