ALPS DNT cells: active senior living with mTOR

作者：Allen Carl E^*

来源：Blood, 2016, 128(2): 152-152.

DOI：10.1182/blood-2016-05-713032

In this issue of Blood, Volkl and colleagues report extended phenotypic and functional analysis of double-negative T cells in autoimmune lymphoproliferative syndrome (ALPS), and find that these cells not only resist cell death but also maintain increased mitotic activity dependent on mechanistic target of rapamycin (mTOR) signaling.(1)

• 出版日期2016-7-14