Phenylselenylation of Ethers using Diphenyl Diselenide-Tributylphosphine-Molecular Oxygen System under Mild Reaction Conditions

作者：Sano Ryota; Kudo Asaki; Tsubogo Tetsu; Uchiro Hiromi^*

来源：Asian Journal of Organic Chemistry, 2018, 7(4): 724-728.

DOI：10.1002/ajoc.201800026

• C(sp(3))-H activation
• metal and peroxide-free conditions
• phenylselenylation of ethers
• tributylphosphonium peroxide radical

An efficient method for phenylselenylation of ethers using a diphenyl diselenide-tributylphosphine-molecular oxygen system has been successfully developed. The reactions proceed under mild conditions in good to high yield. A plausible reaction mechanism for the phenylselenylation via C(sp(3))-H activation was also proposed, and a tributylphosphonium peroxide radical was assumed as an important intermediate in the C(sp(3))-H activation.

• 出版日期2018-4