科研之友
微信
新浪微博
Facebook
分享链接
摘要
Objective: To evaluate sex differences in left ventricular (LV) function after an ultramarathon, and the association of vascular and training indices with the magnitude of exercise-induced cardiac fatigue. Design: Descriptive field study. Setting: Fat Dog 100 Ultramarathon Trail Race, Canada. Participants: Thirty-four (13 women) recreational runners (aged 28-56 years). Interventions: A 100-km or 160-km mountain marathon. Main Outcome Measures: Baseline baroreceptor sensitivity, heart rate variability, and arterial compliance; Pre-exercise and postexercise echocardiographic evaluations of LV dimensions, volumes, Doppler flow velocities, tissue velocities, strain, and strain rate. Results: Finishers represented 17 men (44.8 +/- 6.6 years) and 8 women (45.9 +/- 10.2 years; P = 0.758). After ultraendurance exercise, significant reductions (P < 0.05) in fractional shortening (men: 40.9 +/- 6.9 to 34.1 +/- 7.6%; women: 42.5 +/- 6.5 to 34.6 +/- 7.9%) diastolic filling (E/A, men: 1.28 +/- 0.68 to 1.26 +/- 0.33; women: 1.55 +/- 0.51 to 1.30 +/- 0.27), septal and lateral tissue velocities (E'), and longitudinal strain (men: 221.02 +/- 1.98 to 218.44 +/- 0.34; women: 220.28 +/- 1.90 to 218.44 +/- 2.34) were observed. Sex differences were found for baseline cardiac structure and global function, peak late transmitral flow velocity, and estimates of LV filling pressures (P < 0.05). Regression analysis found that higher baseline arterial compliance was associated with lower reductions in cardiac function postexercise, to which sex was a significant factor for E' of the lateral wall. Faster race pace and greater lifetime ultramarathons were associated with lower reductions in LV longitudinal strain (P < 0.05). Conclusions: Cardiac responses after an ultramarathon were similar between men and women. Greater evidence of exercise-induced cardiac fatigue was found to be associated with lower baseline arterial compliance and training status/experience.
- 出版日期2015-5
