摘要
A practical and novel process for the decarboxylative fluorination of -ketoacids in water in the presence of phase transfer catalyst has been developed, affording a series of -fluoroketones in good to excellent yields. Furthermore, a preliminary investigation for the catalytic asymmetric transformation was performed and a proposed mechanistic pathway for this catalytic process was proposed.
- 出版日期2015-8-10
- 单位天津大学