Neuroprotection: The Emerging Concept of Restorative Neural Stem Cell Biology for the Treatment of Neurodegenerative Diseases

作者：Carletti Barbara^*; Piemonte Fiorella; Rossi Ferdinando

来源：Current Neuropharmacology, 2011, 9(2): 313-317.

DOI：10.2174/157015911795596603

• Neural stem cells
• neurodegenerative disorders
• neuroprotection
• neurotrophic factors
• oxidative stress

During the past decades Neural Stem Cells have been considered as an alternative source of cells to replace lost neurons and NSC transplantation has been indicated as a promising treatment for neurodegenerative disorders. Nevertheless, the current understanding of NSC biology suggests that, far from being mere spare parts for cell replacement therapies, NSCs could play a key role in the pharmacology of neuroprotection and become protagonists of innovative treatments for neurodegenerative diseases. Here, we review this new emerging concept of NSC biology.

• 出版日期2011-6