Acute effects of caffeine on threat-selective attention: moderation by anxiety and EEG theta/beta ratio

作者:van Son Dana; Schalbroeck Rik; Angelidis Angelos; van der Wee Nic J A; van der Does Willem; Putman Peter
来源:Biological Psychology, 2018, 136: 100-110.
DOI:10.1016/j.biopsycho.2018.05.006

摘要

Background: Spontaneous EEG theta/beta ratio (TBR) probably marks prefrontal cortical (PFC) executive control, and its regulation of attentional threat-bias. Caffeine at moderate doses may strengthen executive control through increased PFC catecholamine action, dependent on basal PFC function.
Goal: To test if caffeine affects threat-bias, moderated by baseline frontal TBR and trait-anxiety.
Methods: A pictorial emotional Stroop task was used to assess threat-bias in forty female participants in a crossover, double-blind study after placebo and 200 mg caffeine.
Results: At baseline and after placebo, comparable relations were observed for negative pictures: high TBR was related to low threat-bias in low trait-anxious people. Caffeine had opposite effects on threat-bias in low trait-anxious people with low and high TBR.
Conclusions: This further supports TBR as a marker of executive control and highlights the importance of taking baseline executive function into consideration when studying effects of caffeine on executive functions.

  • 出版日期2018-7