A 28-year-old woman with fever, rash, and pancytopenia

作者:Ochoa Sebastian*; Cheng Kyle; Fleury Christine M; Luccioli Stefano; Bellanti Joseph A
来源:Allergy and Asthma Proceedings, 2017, 38(4): 322-327.
DOI:10.2500/aap.2017.38.4042

摘要

A 28-year-old Hispanic woman was admitted to the hospital with fever, sore throat, arthralgia, and a generalized rash of 2 weeks' duration. Her medical history was significant for various food and medication allergies. Multiple antibiotics were given for suspected infection, and she subsequently developed a new skin rash, acute liver injury, eosinophilia, and pancytopenia. Additional studies showed hypertriglyceridemia; elevated interleukin-2 receptor levels; absent natural killer cell activity; and hemophagocytosis in skin, liver, and bone marrow biopsy specimens. Treatment with intravenous immunoglobulin and steroids resulted in complete remission.

  • 出版日期2017-8