New 19 alpha-hydroxyursane-type triterpenes from the leaves of Meyna spinosa (= Vangueria spinosa), Rubiaceae

作者：Rudrapaul Prasenjit; Das Niranjan; De Utpal Chandra; Dinda Biswanath^*

来源：Phytochemistry Letters, 2014, 9: 7-10.

DOI：10.1016/j.phytol.2014.03.009

• Meyna spinosa
• Vangueria spinosa
• Rubiaceae
• 19 alpha-Hydroxyursane-type triterpenes

Two new 19 alpha-hydroxyursane-type triterpenes, 2 alpha,3 alpha,19 alpha,24,28-pentahydroxyurs-12-ene (1) and meyanthic acid, 3 beta-acetoxy-2 beta, 19 alpha, 23-trihydroxyurs-12-en-28-oic acid (2) along with one new aliphatic ester, myricyl pentadecanoate (3) and five known compounds, 19 alpha-hydroxyasiatic acid (4), oleanolic acid (5), myricyl alcohol (6), beta-sitosterol (7) and its glycoside (8) were isolated from the methanolic leaf extract of Meyna spinosa Roxb. ex Link (= Vangueria spinosa Roxb., Rubiaceae). The structures of the new compounds were elucidated on the basis of extensive spectroscopic (including 2D NMR) analysis and comparison with literature. Except oleanolic acid, isolation of known compounds was reported for the first time from this plant.

• 出版日期2014-9