科研之友
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摘要
We have formulated 7-ethyl-10-hydroxy camptothecin (SN38) nanocrystals using a novel combination of reversible reactions and pharmaceutical technology. The nanocrystals are taken up more efficiently by cells and accumulate more in tumors than the commercially available camptothecin compound irinotecan (CPT-11), leading to superior anti-tumor efficacy in vitro and in vivo.
- 出版日期2019-3-14
- 单位四川大学
