科研之友
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摘要
An enantioselective transfer hydrogenation reaction of alkynyl ketimine bearing a trifluoromethyl group was accomplished. Chemoselective reduction of ketimine was achieved by the combined use of chiral phosphoric acid and benzothiazoline to give -trifluoromethyl propargylamine in good to high yields and with excellent enantioselectivity.
- 出版日期2018-7
