Acute myocardial/cerebral infarction as first/relapse manifestation in one acute promyelocytic leukemia patient

作者：Li, Ying; Suo, Shanshan; Mao, Liping; Wang, Lei; Yang, Chunmei; Xu, Weilai; Lou, Yinjun; Mai, Wenyuan^*

来源：International Journal of Clinical and Experimental Medicine, 2015, 8(8): 14210-14213.

• Acute promyelocytic leukemia
• initial symptom
• acute myocardial infarction
• cerebral infarction

In the clinical setting, bleeding is a common manifestation of acute promyelocytic leukemia (APL), whereas thrombosis is relatively rare, especially as an initial symptom. Here, we report an unusual case of APL with acute myocardial infarction as the first manifestation and cerebral infarction as the relapse manifestation in a healthy young woman. This unique case emphasizes that a thrombotic event could be the first manifestation of an underlying hematological disorder such as APL and could also be a sign of relapse. Rapid detection of the underlying disorder and the timely use of anticoagulation therapy and ATRA are crucial for preventing further deterioration of the disease and saving the patient's life.

• 出版日期2015
• 单位浙江大学