New strategies of systemic lupus erythaematosus

作者:Sah Om Shankar Prasad; Liu Zhangsuo*
来源:Life Science Journal-Acta Zhengzhou University Overseas Edition, 2009, 6(1): 47-51.

摘要

Systemic lupus erythematosus (SLE) is an autoimmune chronic systemic disease which can involve several organs such as skin, lungs, brain and heart. Pulmonary manifestations of SLE can include a wide spectrum of diseases such as pleuritis, pneumonia, pulmonary embolism, pneumothorax and pulmonary haemorrhage. The aim of new strategies is to induce and maintain clinical remission. The standard forms of therapy for SLE have not changed in this year, but the new drugs are induced specially immunosuppresants, mycophenolate mofetil, Cyclosporine, biological agents, Rituximab, LJP394, nucleoside analogues, blockade of constimulatory molecule, immunoadsorption and others for better management of the disease. The new drugs most likely mycophenolate mofetil and biological agents are expected to help the patients with SLE to improve life with more efficacies and less toxicity. [Life Science Journal. 2009; 6(1): 47 - 51] (ISSN: 1097 - 8135).