Association Between Allergies and Psychiatric Disorders in Patients Undergoing Invasive Procedures

作者：Aberle Dwight; Wu Stephanie E; Oklu Rahmi; Erinjeri Joseph; Deipolyi Amy R^*

来源：Psychosomatics, 2017, 58(5): 490-495.

DOI：10.1016/j.psym.2017.03.015

• Allergy
• Psychiatric disorder
• Pain
• Sedation
• Invasive procedure

Background: Associations between allergies and psychiatric disorders have been reported in the context of depression and suicide; psychiatric disorders may affect pain perception. Objective: To investigate the relationship of allergies with psychiatric disorders and pain perception in the context of invasive procedures, speccally during tunneled hemodialysis catheter placement. Methods: We idented 89 patients (51 men, 38 women), mean age 66 years (range: 23-96), who underwent tunneled hemodialysis catheter placement (112014-212015), recording numeric rating scale pain scores, medications, psychiatric history, allergies, and smoking status. Results: Of 89 patients, 47 patients had no allergies, and 42 had >= 1 allergy. Patients with allergies were more likely to have a pre-existing psychiatric disorder compared to those without allergies, odds ratio 2.6 (95% CI: 1.0-6.8). Having allergies did not affect procedural sedation or post procedural pain scores. Multiple logistic regression with age, sex, smoking, presence of allergies, psychiatric history, inpatientl outpatient status, procedure time, and procedural sedation administration as inputs and post procedural pain as the outcome showed that the only independent predictor was receiving procedural sedation (P = 0.005). Conclusions: Findings corroborate anecdotal reports of allergies as a marker for psychiatric history. However, having allergies was not associated with increased pain or need for more sedation. Further studies could prospectively assess whether allergies and psychiatric disorders affect patientldoctor perceptions beyond pain during invasive procedures.

• 出版日期2017-10