Mitochondrial Biogenesis: Cell-Cycle-Dependent Investment in Making Mitochondria

作者:Shiota Takuya; Traven Ana; Lithgow Trevor*
来源:Current Biology, 2015, 25(2): R78-R80.
DOI:10.1016/j.cub.2014.12.006

摘要

Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.