Algorithm for Correcting the Keratometric Error In the Estimation of the Corneal Power In Keratoconus Eyes after Accelerated Corneal Collagen Crosslinking

作者：Pinero David P^*; Camps Vicente J; Caravaca Arens Esteban; de Fez Dolores; Blanes Mompo Francisco J

来源：Journal of Ophthalmology, 2017, 2017: 8529489.

DOI：10.1155/2017/8529489

Purpose. To analyze the errors associated to corneal power calculation using the keratometric approach in keratoconus eyes after accelerated corneal collagen crosslinking (CXL) surgery and to obtain a model for the estimation of an adjusted corneal refractive index (n(kadj)) minimizing such errors. Methods. Potential differences (delta P-c) among keratometric (P-k) and Gaussian corneal power (p(c)(Gauss)) were simulated. Three algorithms based on the use of n(kadj) for the estimation of an adjusted keratometric corneal power (P-kadj) were developed. The agreement between P-k(1.3375) (keratometric power using the keratometric index of 1.3375), P-c(gauss), and P-kadj was evaluated. The validity of the algorithm developed was investigated in 21 keratoconus eyes undergoing accelerated CXL. Results. P-k(1.3375) overestimated corneal power between 0.3 and 3.2 D in theoretical simulations and between 0.8 and 2.9 D in the clinical study (delta P-c). Three linear equations were defined for n(kadj) to be used for different ranges of r(1c). In the clinical study, differences between P-kadj and P-c(gauss) did not exceed +/- 0.8 D n(k)= 1.3375. No statistically significant differences were found between P-kad and P-c(gauss) (p >0.05) and P-k(1.3375) and P-kadj (p<0.001). Conclusions. The use of the keratometric approach in keratoconus eyes after accelerated CXL can lead lo significant clinical errors. These errors can be minimized with an adjusted keratometric approach.

• 出版日期2017