NOVEL OCTAPEPTIDE AS AN ASYMMETRIC CATALYST FOR MICHAEL REACTION IN AQUEOUS MEDIA

作者:Bayat Saadi; Abdulmalek Emilia; Tejo Bimo Ario; Salleh Abu Bakar; Normi Yahaya M; Rahman Mohd Basyaruddin Abdul*
来源:Synthetic Communications, 2013, 43(23): 3130-3140.
DOI:10.1080/00397911.2012.762686

摘要

In this work, three forms of a novel octapeptide have been evaluated as asymmetric catalysts for the Michael reaction. Low quantity catalyst loading, ecofriendly solvents, and reusability of organocatalyst successfully applied to attain excellent yields and moderate enantioselectivities in the Michael reaction. [Supplementary materials are available for this article. Go to the publisher%26apos;s online edition of Synthetic Communications (R) for the following free supplemental resources: Full experimental and spectral details.]

  • 出版日期2013-12-2