A Cu(I)-catalyzed C-H alpha-amination of esters. Direct synthesis of hydantoins

作者:Zhao Baoguo; Du Haifeng; Shi Yian*
来源:Journal of the American Chemical Society, 2008, 130(23): 7220-+.
DOI:10.1021/ja802242h

摘要

This paper describes a novel intermolecular alpha-amination process of esters using CuCl as catalyst and di-tert-butyldiaziridinone as nitrogen source. A variety of hydantoins can be formed effectively under mild reaction conditions.

  • 出版日期2008-6-11