科研之友
微信
新浪微博
Facebook
分享链接
摘要
exo/endo-Hydroxylated cyclohexenones are essential synthetic intermediates for a variety of biologically active compounds. However, methods that lead to efficient and selective preparation of exo/endo-hydroxylated cyclohexenones remain to be established. Herein, we report the practical and scalable synthesis of exo/endo-hydroxylated cyclohexenones from readily available 2,6-diketosulfoxides. We demonstrate that endo and exo geometric isomers of hydroxylated cyclohexenones can be obtained by simple modification of the reaction conditions.
- 出版日期2018-5
