Ultrasound-guided cable-free 13-gauge vacuum-assisted biopsy of non-mass breast lesions

作者：Seo Jiwoon; Kim Sun Mi; Jang Mijung; La Yun Bo; Lee Soo Hyun; Kim Eun Kyu; Kang Eunyoung; Park So Yeon; Moon Woo Kyung; Choi Hye Young; Kim Bohyoung

来源：PLos One, 2017, 12(6): e0179182.

DOI：10.1371/journal.pone.0179182

Purpose
To compare the outcomes of ultrasound-guided core biopsy for non-mass breast lesions by the novel 13-gauge cable-free vacuum-assisted biopsy (VAB) and by the conventional 14gauge semi-automated core needle biopsy (CCNB).
Materials and methods
Our institutional review board approved this prospective study, and all patients provided written informed consent. Among 1840 ultrasound-guided percutaneous biopsies performed from August 2013 to December 2014, 145 non-mass breast lesions with suspicious microcalcifications on mammography or corresponding magnetic resonance imaging finding were subjected to 13-gauge VAB or 14-gauge CCNB. We evaluated the technical success rates, average specimen numbers, and tissue sampling time. We also compared the results of percutaneous biopsy and final surgical pathologic diagnosis to analyze the rates of diagnostic upgrade or downgrade.
Results
Ultrasound-guided VAB successfully targeted and sampled all lesions, whereas CCNB failed to demonstrate calcification in four (10.3%) breast lesions with microcalcification on specimen mammography. The mean sampling time were 238.6 and 170.6 seconds for VAB and CCNB, respectively. No major complications were observed with either method. Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia (ADH) lesions were more frequently upgraded after CCNB (8/23 and 3/5, respectively) than after VAB (2/26 and 0/4, respectively P = 0.028).
Conclusion
Non-mass breast lesions were successfully and accurately biopsied using cable-free VAB. The underestimation rate of ultrasound-detected non-mass lesion was significantly lower with VAB than with CCNB.

• 出版日期2017-6-19