Efficient C-C double-bond formation reaction via a new synthetic strategy: A self-sorting tandem reaction

作者:Yin Guodong; Zhou Baohan; Meng Xianggao; Wu Anxin*; Pan Yuanjiang
来源:Organic Letters, 2006, 8(11): 2245-2248.
DOI:10.1021/ol060541e

摘要

A novel and efficient carbon-carbon double-bond formation reaction via coupling of aryl or heteroaryl methyl ketones has been developed. A dimethyl sulfoxide-iodine-CuO system was proven to be efficient for this reaction and afforded the expected products in good yields. A new synthetic strategy, a self-sorting tandem reaction, was involved in this type of reaction and was presented for the first time.